Child with True Hermaphroditism
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چکیده
True hermaphrodites possess both ovarian and testicular tissues which may be present in separate gonads or combined in an ovotestis. External and internal genitalia are ambiguous and variable, though a prominent penial structure is usual. Chromosome examination of true hermaphroditism has revealed an XX sex chromosome complement in the majority of cases, but the XY complement and different mosaic constitutions have also been described (see reviews of Miller, 1964; Dewhurst et al., 1965; Turpin and Lejeune, 1965; Yunis, 1965; Mittwoch, 1967). The most interesting mosaic constitution is XX/XY which has been reported in four true hermaphrodites (Gartler, Waxman, and Giblett, 1962; Grouchy et al., 1964; Overzier, 1964; Br0gger and Aagenaes, 1965). We describe a further true hermaphrodite who has both XX and XY cells.
منابع مشابه
True Hermaphrodite: A Case Report
True hermaphrodite is one of the rarest variety of disorders of sexual differentiation (DSD) and represents only 5% cases of all. A 3-year-old child presented with left sided undescended testis and penoscrotal hypospadias. Chordee correction was performed 18 months back, elsewhere. At laparotomy Mullerian structures were present on left side. On right side testis was normally descended into the...
متن کاملHermaphrodite with Mosaic
SIR,-In a recent review de Grouchy 1 compiles the following karyotypes described in true hermaphroditism: 46 XX, 46 XY, 46 XX/46 XY, 45 XO/46 XY, 46 XX/47 XXY, 46 XX/47 XXX, 46 XX/46 XY/45 XO, 46 XX/47 XXY/ 49 XXYYY, and 45 XO/46 X isoY/47 XY isoY. We have studied the chromosomes of a true hermaphrodite with a new mosaicism, 46 XX/46 XY/47 XXY, which might throw some light on the possible multi...
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متن کاملUnusual dual genital duct remnants in true hermaphroditism.
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تاریخ انتشار 2006